Chemical constituents from the roots of Ranunculus ternatus and their inhibitory effects on Mycobacterium tuberculosis.

نویسندگان

  • Ke-Zhong Deng
  • Ying Xiong
  • Bin Zhou
  • Yong-Mei Guan
  • Yong-Ming Luo
چکیده

Two new benzophenones, methyl (R)-3-[2-(3,4-dihydroxybenzoyl)-4,5-dihydroxyphenyl]-2-hydroxypropanoate (1) and n-butyl (R)-3-[2-(3,4-dihydroxybenzoyl)-4,5-dihydroxyphenyl]-2-hydroxypropanoate (2), were isolated from the roots of Ranunculus ternatus along with the two known compounds vanillic acid (3) and gallic acid (4). Their structures were elucidated by physical and spectroscopic analysis. In addition, compound 1 exhibited obvious activity against tuberculosis, while the activity of a 1:1 mixture of compound 1 plus 4 is better than that of 1 alone.

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عنوان ژورنال:
  • Journal of Asian natural products research

دوره 8 1-2  شماره 

صفحات  -

تاریخ انتشار 2006